Intended Use

Feline Pancreatic Lipase Rapid Test is a lateral flflow immunoassay intended for the determination of pancreas-specifific lipase levels in feline serum or plasma.

Contents

Specifications

Operation

Results

Pathology Introduction 

Feline Pancreatic Lipase tend to present with subclinical symptoms， often as part of a systemic disease, such as toxoplasmosis, or associated with inflammatory bowel disease.

The clinical symptoms and clinicopathological features of dogs with acute pancreatitis are the same as those reported for experimental models and some natural-onset cats, but cats are more sensitive.

At least 2 types of severe pancreatitis in cats can be classified on the basis of histopathological changes in the pancreas:

Acute necrotic type: more common

Acute septic type: less common, often occurring in young cats ( the average is 3.5 years old)

Typical signs in both types of affected cats are lethargy, loss of appetite, vomiting, dehydration, weight loss, jaundice and hypothermia. Because the history and physical findings of affected cats are non-specific, confirming the diagnosis before death is difficult.

Recurrent and chronic pancreatitis

In chronic pancreatitis or pancreatic insufficiency, the lack of trypsin, esterase and amylase results in feces containing indigestible muscle fibres, fat and starch.

Most cats with chronic pancreatitis are elderly domestic shorthair cats. Clinical signs present in more than 50% of affected cats include: loss of appetite, weight loss and intermittent vomiting. Physical examination results are variable, and the lack of specificity of the symptoms is similar to that of inflammatory colorectal diseases, so it is not easy to diagnose.

During recovery from acute pancreatitis, some cats appear to have recurrent acute pancreatitis, a condition known as recurrent pancreatitis.

Means of detection

AMY (amylase) is not specific for diagnosing pancreatitis. It may be informative only when it is markedly elevated.

Metabolic pathway of amylase and lipase: released from pancreas into peritoneal fluid, absorbed into bloodstream via lymphatic vessels of the diaphragm. Partially inactivated by renal degradation. Lipase activity should be interpreted with caution, as pancreatitis is only possible if the value is elevated 3-5 times the upper limit of the reference value. Currently ITGEN’s Feline Pancreatitis Rapid Test is used to test pancreatic lipase levels in pets and is able to quickly and accurately detect pancreatic levels in cats within 5-10 minutes.

Treatment Options

Diagnostic and therapeutic approaches similar to those used for canine pancreatitis are recommended, except for prolonged fasting.

Because prolonged fasting may precipitate hepatic lipid deposition syndrome in cats, immediate establishment of an enteral feeding tube (e.g., duodenostomy or jejunostomy) is recommended when pancreatitis is diagnosed in cats.

Both types of feline acute pancreatitis are serious diseases and are not easily diagnosed, so the prognosis for both is carefully monitored.

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