Feline Panleukopenia virus, feline coronavirus and feline infectious peritonitis virus are three common viruses that cause gastrointestinal disease in cats.

Similarities

Route of transmission:

Direct contact: spread through contact with body fluids (e.g. faeces, saliva) of infected animals.

Indirect contact: spread through contact with contaminated environments or objects.

Symptoms:

Gastrointestinal symptoms: diarrhoea, vomiting, loss of appetite.

Systemic symptoms: fever, lethargy, weight loss, dehydration.

Preventive Measures:

Vaccination: vaccination against feline distemper virus and feline coronavirus.

Good hygiene habits: keep the environment clean, avoid contact with infected animals.

Differences

Pathogen:

Feline Panleukopenia virus: caused by feline panleukopenia virus (, a fine virus.

Feline Coronavirus (FCoV): includes enteric type (FECV) and peritonitis type (FIPV), FIPV is mutated from FECV.

Feline infectious peritonitis virus (FIPV): a pathogenic variant of feline coronavirus.

Specific symptoms:

Feline Panleukopenia virus:

Acute symptoms: high fever, leukopenia, severe vomiting and diarrhoea (may contain blood).

Other symptoms: dehydration, anaemia, high rate of infection and mortality in young cats.

Feline Coronavirus (FCoV):

Enteric type (FECV): mild diarrhoea, vomiting, less severe symptoms.

Peritonitis type (FIPV): severe ascites, pleural fluid, fever, jaundice, loss of appetite, usually fatal.

Feline Infectious Peritonitis Virus (FIPV):

Dry type FIP: ocular signs (e.g. iritis, retinal haemorrhages), neurological signs (e.g. seizures, ataxia).

Wet FIP: ascites, pleural fluid, fever, jaundice, loss of appetite, usually fatal.

Detection

Feline Panleukopenia virus:

Rapid antigen test: detects viral antigen in faeces using rapid test strips.

PCR test: detects viral DNA with high sensitivity and specificity.

Serological tests: Detection of anti-FPV antibody levels.

Feline Coronavirus (FCoV):

PCR assay: detects viral RNA, especially that of FIPV.

Serological test: detects anti-FCoV antibody levels, but cannot distinguish between FECV and FIPV.

Abdominal/thoracic fluid analysis: detects the characteristic fluid components of FIPV infection, such as high protein content and viscosity.

Feline infectious peritonitis virus (FIPV):

PCR assay: detection of mutant FIPV RNA, especially in ascitic or pleural fluid samples.

Serological test: detects anti-FIPV antibody levels, but does not distinguish between FECV and FIPV.

Abdominal/thoracic fluid analysis: detects the characteristic fluid components of FIPV infection, such as high protein content and viscosity.

Histopathology: detects typical granulomatous inflammation in tissue samples.

Feline Panleukopenia Virus/Coronavirus/Infectious Peritonitis Virus Antigen Combo Rapid Test

Antigenne has developed the Feline Panleukopenia Virus/Coronavirus/Infectious Peritonitis Virus Antigen Combo Rapid Test to help users diagnose gastrointestinal diseases in cats more accurately and develop appropriate treatment and control measures to protect cats. and preventive and control measures to protect the health of cats.